Ahead of the open, the Dow Jones Industrial Average futures pointed to a 0.31% gain, S&P 500 futures signaled a 0.39% rise, while the Nasdaq 100 futures indicated a 0.48% increase.
Markets were jittery amid expectations that the Fed will soon start tapering its USD85 billion-a-month bond buying program.
Investors were awaiting Friday’s U.S. nonfarm payrolls data, with good data set to bolster the dollar further.
Onyx Pharmaceuticals was expected to remain in the spotlight for the second consecutive session, after confirming that it had rejected a purchase offer from Amgen to buy the company in a deal valued at about USD10 billion, sending shares up over 50% on Monday.
Shares slipped 0.10% in pre-market trade.
In the tech sector, Apple shares rose 0.27% in early trading after the iPhone maker filed for an "iWatch" trademark in Japan, implying that the company is working on developing a smartwatch.
Separately, Raymond James raised its rating on the company to "strong buy" from "outperform."
Also among smartphone makers, BlackBerry was likely to remain in focus after several analysts downgraded the stock following the company's disappointing quarterly results.
In company news, Walt Disney Co. extended Robert Iger’s tenure as chief executive officer of the entertainment company to June 2016, delaying his planned succession for 15 months. Shares climbed 0.48% in after-hour trade.
Across the Atlantic, European stock markets were lower. The EURO STOXX 50 dropped 0.58%, France’s CAC 40 declined 0.49%, Germany's DAX retreated 0.93%, while Britain's FTSE 100 slid 0.43%.
During the Asian trading session, Hong Kong's Hang Seng Index dropped 0.70%, while Japan’s Nikkei 225 Index jumped 1.78%.
Later in the day, the U.S. was to produce official data on factory orders.
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